Photoradiation of Malignancy (Cancer)

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Hematoporphyrin subordinate (HPD) is a medication which was created to be consumed by threatening cells and possibly becomes dynamic when presented to light. It is usually used to distinguish and restrict diseases as when it is under initiation of blue light the red fluorescence of the dangerous cancer (because of the HPD) can be noticed easily.

The mix of HPD with red light (photoradiation) has been utilized on different threatening growths remembering dangerous melanomas and carcinomas for a scope of various organs including the bosom and colon. This type of therapy delivers a singlet oxygen through the photodynamic process; where the oxygen particle exists in an electronically invigorated state. The singlet oxygen is a cytotoxic specialist which holds the capacity to destroy harmful cells by forestalling both nucleic corrosive and protein synthesis. The therapy interaction likewise uses HPD's ability of collecting at more elevated levels in harmful tissues contrasted with most other tissues.

SURGERY OF MALIGNANCY (CANCER)

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Medical procedure/Surgery can help oversee or treat harm by either eliminating the growth, restricting it and additionally deciding if there has been a spread to other organs. When undertaking a medical procedure for danger, there are six significant goals which are considered. These incorporate "counteraction of malignancy, analysis and arranging of sickness, illness fix, cancer debulking, indication vindication and patient rehabilitation".

Careful avoidance of malignant growth generally comprises of eliminating the organ in danger of creating malignancy. This would happen if an individual is inclined to the development of harmful cells because of acquired hereditary transformations and, procured sicknesses.

Post-Transplant Malignancy

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People who go through organ relocate a medical procedure have an expanded danger of creating threat in contrast with the general population. The most widely recognized type of harm being "nonmelanoma skin disease and, posttransplant lymphoproliferative disorders". The various sorts of harm created post-relocate rely upon which organ was transplanted. This is connected to beneficiaries being at a higher danger when presented to conventional danger factors just as, the sort and force of the activity, the span of their immunosuppression post-activity and, the danger of creating oncogenic viral infections.

Signs and Symptoms of Malignancy

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When Malignant cells structure, indications don't normally show up until there has been a critical development of the mass. Once signs and side effects do emerge, they are reliant upon the area, size and kind of harm. As a rule, it is very broad and can be related with different sicknesses or illnesses and in this manner, can be hard to analyze or can be misdiagnosed. 

Signs and Symptoms are incorporate recognizable or quantifiable perspectives, for example, weight reduction (easily), a fever or uncommon bleeding. On the other hand, indications are felt inside by the individual like weakness or changes in appetite. An overall rundown of normal signs and side effects incorporates torment (migraines or bone hurts), skin changes (new moles or knocks), hacking and strange bleeding. There are likewise signs and manifestations explicit to females including stomach torment and bulging or bosom changes i.e., the arrangement of a lump. Signs and indications explicit to men incorporate agony or developments in the scrotum or trouble urinating.

Classification of Malignancy (Cancer)

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Harm in diseases is described by anaplasia, obtrusiveness, and metastasis. Malignant growths are likewise portrayed by genome flimsiness, so tumors, as evaluated by entire genome sequencing, much of the time have somewhere in the range of 10,000 and 100,000 changes in their whole genomes. Cancers as a rule show cancer heterogeneity, containing numerous subclones. They additionally as often as possible have decreased articulation of DNA fix compounds due to epigenetic methylation of DNA fix qualities or adjusted microRNAs that control DNA fix quality articulation.

OSTEOSARCOMA - CANCER

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An osteosarcoma (OS) or osteogenic sarcoma (OGS) (or essentially bone malignancy), is a harmful growth in a bone. In particular, it is a forceful threatening neoplasm that emerges from crude changed cells of mesenchymal beginning (and along these lines a sarcoma) and that shows osteoblastic separation and produces harmful osteoid.

Osteosarcoma is the most widely recognized histological type of essential bone sarcoma. It is generally predominant in teens and youthful grown-ups.

TYPES OF CANCER

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• BONE AND MUSCLE SARCOMA CANCER

• BRAIN AND NERVOUS SYSTEM CANCER

• BREAST CANCER

• ENDOCRINE SYSTEM CANCER

• EYE CANCER

• GASTROINTESTINAL CANCER 

• GENITOURINARY AND GYNECOLOGIC CANCER

•  HEAD AND NECK CANCER

• HEMATOPOIETIC CANCER

• SKIN CANCER

• THORACIC AND RESPIRATORY CANCER

• HIV/AIDS CANCER

CAUSES OF CANCER

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Tobacco is the major cause and reason of Cancer. Approximately, 22% of death caused by Tobacco. About 10% are coz of obesity, poor-diet, lack of physical activity, excessive intake of alcohol, substance-use or addiction. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are coz of infections such as Helicobacter pylori, hepatitis-B, hepatitis-C, human papillomavirus infection, Epstein-Barr virus and human immunodeficiency virus (HIV).

Approximately, 5% - 10% of cancers are due to inherits genetic defects. Cancer can be detected by certain Signs and Symptoms or screening tests. It is then typically further investigated by medical imaging, and confirmed by biopsy.

Prevention of Coronary Artery Disease

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Approximately, 90% of cardiovascular disease may be preventable if established risk factors are ignored. Prevention of Coronary Artery Disease includes adequate physical exercise, decreasing obesity, treating high blood-pressure, feeding and eating a healthy diet, decreasing cholesterol levels and stopping smoking, alcohol, substance-use and addiction.

Medications and exercises are equally balanced and effective. High-level of physical activity leads to reduction in the risk of coronary artery disease by approximately 25%.

How did Coronary Artery Disease (CAD) affect/influence/impact to the people ?

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In 2015, Coronary Artery Disease (CAD) influenced 110 million people which leads to 8.9.million deaths. It makes up 15.6% of all deaths, by making it the most common cause and reason of death World-Wide. The risk of Coronary Artery Disease (CAD), for a given age decreased from 1980 to 2010, especially in developed countries. The number of cases of Coronary Artery Disease (CAD), also decreased from 1990 to 2010.

In the United States in 2010, approximately 20% of those people over 65 had Coronary Artery Disease (CAD), where currently, it is 7% of those people 45 to 64, and 1.3 % of those people 18 to 45.

These rates were common among men than women of a given a particular age. 

TYPES OF HEART DISEASES

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• CORONARY ARTERY DISEASE (CAD)

• HEART ARRHYTHMIAS

• HEART FAILURE

• HEART VALVE DISEASE

• PERICARDIAL DISEASE

• CARDIOMYOPATHY (HEART MUSCLE DISEASE)

• CONGENTIAL HEART DISEASE 

• PULMONARY STENOSIS

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Treatment for COVID-19 (Corona-Virus)

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Subsequently, Vaccination is not a particularly and effective treatment or cure. In other words, Vaccination cannot considered to be a permanent solution for the pandemic COVID-19 (Corona-Virus). One - year into the pandemic, highly effective and beneficial vaccines have been introduced and are starting to slow the causes of SARS-CoV-2; however for those awaiting for vaccination, as well as for the estimated millions of immunocompromised persons who are unlikely to respond robustly to vaccination, treatment remain important. Thus, the lack of progress developing effective and beneficial treatments means that the cornerstone of management of COVID-19 has been supportive care, which includes treatment to relieve signs and symptoms, fluid therapy, oxygen support and prone positioning as required, and meditations or devices to support other adversely influenced vital organs.  

Most of the COVID-19 cases, are mild. In these situations, supportive and healthcare includes treatments and meditation such as paracetamol or NSAID's to relieve signs and symptoms of fever, body-aches, cough, proper intake of fluids, rest and nasal breathing.

"Good personal hygiene and healthy diet are also recommended."

THIRD WAVE - Spanich Flu

 Third wave of 1919 :

In January 1919, the third wave of Spanich Flu hit Australia, where it killed around 12,000 people following the lift of maritime quarantine, and then spread quickly through Europe and United States, where it lingered through the spring and until June IN 1919. It primarily affected Spain, Serbia, Mexico and Great Britain; resulting in hundreds of thousands of deaths. It was less severe than the second wave still much more deadly than the initial first wave. In United States, isolated outbreaks occurred in some cities including Los Angeles, New-York city, Memphis, Nashville, San-Francisco and St. Louis. Overall American morality rates were in the tens of thousands during the first six months of 1919's.

......in next article, we'll discuss regarding fourth wave of SPANICH FLU .. 😜 😜 😜

SECOND WAVE - Spanish Flu

Deadly 2nd Wave of late 1918 :

The second wave began in the second half of August 1918, probably Boston and Freetown, Sierra Leone by ships from the Brest, where it had likely arrived with American troops or French recruits for naval training. 

The second wave of the 1918 pandemic was much more deadly than the first. The first wave had resembled typical flu's epidemics; those most at risk were sick and elderly, while younger, healthier people recovered easily. October 1918 was the month was the highest fatality rate of the whole pandemic. In the United States ~2,92,000 deaths were reported between September - December 1918, compared to ~26000 during the same period in 1915. The Netherlands reported 40,000+ deaths from influenza and acute respiratory disease. Mumbai reported ~15,000 deaths in a population of 1.1 million. The 1918 flu pandemic in India was especially deathly with the estimated 12.5-20 million deaths in the first quarter alone.

.....in next article we'll discuss regarding 3rd wave of SPANICH FLU... 😜 😜 😜

PANDEMIC DISEASE

A Pandemic disease is an epidemic, infestation or outbreak of infectious, toxic and communicable disease that spread and expand across a enormous area, for instance numerous continents, internationally and globally affecting a considerable and significant number of people. This globally endemic disease with a stable number of infected people is not a pandemic. 

In human history, there have been number of pandemics of diseases such as small-pox; the most deadly, tragic and incurable pandemic experienced in history/ancient time, was the "Black death" (was known for plaque), which was killed 75-200 million people worldwide in 14th century. It was caused by the bacterium yersinia pesttis and may also caused by septicaemic or pneumonia plaques. 

In 1918, a pandemic which affected the people worldwide, a Spanish Flu, also known as the Great influenza epidemic or 1918 influenza pandemic, was exceptionally deadly life-threatening universally influenza pandemic caused by H1N1 influenza virus. The premature cases was found in France, Germany and United kingdom in April. After 2 years, approximately, two-third of population around 500 million world-wide infected, was infected in four successive waves.

Contemporarily, pandemics include Tuberculosis, HIV/AIDS & COVID-19. 

Coronavirus disease 2019 (COVID-19) is deadly epidemic disease spread by severe acute respiratory syndrome coronavirus 2(SARS-COV 2). It's mainland, engendered and implanted found in Wuhan, China, December 2019. This disease has since caused globally and internationally, leading to ongoing pandemic - it's about to 3rd wave come.

Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a range and stretch of condition caused by infection with the human immunodeficiency virus (HIV), a retrovirus. These symptoms may be experienced or notices by earlier stage or may suffer a brief period of influenza-like symptoms.

Tuberculosis (TB), is a infectious disease generally caused by Mycobacterium tuberculosis (MTB) bacteria. It mainly affects the lungs or may influence other parts of the body.

.......in next articles, we'll discuss in details on theses topics.... 😋 😋 😋