Genetically engineered mice to study metastasis

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Genetically engineered mice are built to version human phenotypes and pathologies. Mutant mice might also consist of transgenes the use of unique shipping techniques:

• The use of bacteria-derived tetracycline-inducible machine permitting the switching on or off (Tet-On/Tet-Off gadget)

• Targeted mutations with the aid of knock in gene and knock out sequence with the aid of the usage of Cre-Lox recombination gadget

• Introduction of unfashionable viral mutations

• Introduction of chemically prompted mutations