Fluorescent imaging, Radioisotopic imaging and MRI Imaging of Mouse models of breast cancer metastasis

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• Fluorescent imaging

Intravital microscopy with multi photon excitation is a technique to visualize genetically engineered cells without delay in vivo. Multi step metastatic cascades may be visualized with the aid of labelling with precise fluorescent color below fluorescence microscope.

• Radioisotopic imaging

Positron emission tomography (PET), unmarried photon emission computed tomography (SPECT) and computed tomography (CT) had been used to examine the efficiency of these in vivo imaging for detecting lesions at an early degree and to evaluate the response to chemotherapy.

• MRI Imaging

Magnetic resonance imaging requires the usage of nano-debris(liposomes) and an MRI evaluation agent known as gadolinium. The debris have been then positioned in vesicles via a polycarbonate membrane filter. The nano-debris are injected into the metastases advanced mice, and left there for 24 hours. These mice are then scanned, and within the imaging software program there are accumulations of these particles in sure regions where cells have metastasized.