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Another tool to take a look at breast cancer metastasis is to search for circulating tumor cells in transgenic mice e.G. Mouse mammary tumor virus (MMTV)-PyMT mice can reply to various remedies in losing tumor cells inside the blood leading to lung metastasis. Not handiest in blood however cells may be detected in bone marrow e.G. Cytokeratin-fantastic cells inside the bone marrow of MMTV-pyMT and MMTV-Neu transgenic mice were recognized however now not inside the wild type controls.
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