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The pineal gland produces the hormone melatonin which performs a function in regulating circadian rhythms. A pinealoma may also disrupt production of this hormone, and insomnia can also result.
Frequently, paralysis of upward gaze at the side of several ocular findings inclusive of convergence retraction nystagmus and eyelid retraction additionally known as Collier's sign and Light Near Dissociation (student accommodates but doesn't react to light) are acknowledged collectively as Parinaud's syndrome or Dorsal Mid-brain syndrome, are the best bodily signs visible. This is caused by the compression of the vertical gaze center in the midbrain tectum at the level of the superior colliculus and cranial nerve III. Work-up usually consists of Neuro-imaging as seen at the proper.
A pinealoma may additionally motive interruption of hypothalamic inhibiting pathways, every so often leading to beta-hCG secretion and consequent Leydig's cell stimulation (endocrine syndrome).
Other signs and symptoms may include hydrocephalus, gait disturbances, and precocious puberty.
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