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Adenomas of the anterior pituitary gland are a main medical feature of multiple endocrine neoplasia kind 1 (MEN1), an extraordinary inherited endocrine syndrome that affects 1 person in every 30,000. MEN reasons diverse combinations of benign or malignant tumors in diverse glands in the endocrine machine or may additionally cause the glands to end up enlarged without forming tumors. It regularly affects the parathyroid glands, pancreatic islet cells, and anterior lobe of the pituitary gland. MEN1 may additionally purpose non-endocrine tumors inclusive of facial angiofibromas, collagenomas, lipomas, meningiomas, ependymomas, and leiomyomas. Approximately 25 percentage of patients with MEN1 increase pituitary adenomas.
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