The first symptoms of neuroblastoma are often indistinct, making prognosis tough. Fatigue, lack of appetite, fever, and joint pain are common. Symptoms rely on number one tumor locations and metastases if present:
- In the abdomen, a tumor may also motive belly distension and constipation.
- A tumor within the chest may additionally purpose respiration problems.
- A tumor urgent at the spinal wire may reason weakness, hence an incapability to face, crawl, or stroll.
- Bone lesions in the legs and hips may additionally purpose pain and limping.
- A tumor in the bones around the eyes or orbits may purpose distinct bruising and swelling.
- Infiltration of the bone marrow might also reason pallor from anemia.
Neuroblastoma regularly spreads to different parts of the frame before any signs are apparent, and 50 to 60% of all neuroblastoma cases gift with metastases.
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