Treatment of Oligodendroglioma

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Oligodendrogliomas are normally felt to be incurable using present day remedies. However as compared to the extra not unusual astrocytomas, they're slowly growing with extended survival. In one series, median survival instances for oligodendrogliomas had been 11.6 years for grade II.
However, such figures can be misleading seeing that they do no longer issue inside the varieties of remedy nor the genetic signature of the tumors. A latest have a look at analyzed survival primarily based on chromosomal deletions and the consequences of radiation or chemotherapy as remedy, with the subsequent consequences (both low-grade and anaplastic oligodendrogliomas): 1p/19q deletion with radiation = 121 months (suggest), 1p/19q deletion with chemotherapy = over 160 months (imply now not yet reached), no 1p/19q deletion with radiation = 58 months (mean), and no 1p/19q deletion with chemotherapy = 75 months (suggest).
Because of the indolent nature of this tumor and the capability morbidity associated with neurosurgery, chemotherapy and radiation therapy, most neurooncologists will first of all pursue a direction of watchful waiting and deal with sufferers symptomatically. Symptomatic remedy frequently consists of the use of anticonvulsants for seizures and steroids for mind swelling.